All Your Questions Answered About IsaBiome


The new IsaBiome™ Daily Digestive Health System is designed as a complete solution consisting of  probiotics and digestive enzymes to support your gut microbiome and better digestive health. The system is available as designed for “conventional” or “vegetarian” diets.

To learn more about IsaBiome, please be sure to check out our toolkit. In the toolkit, you’ll learn what makes IsaBiome different and how to use the products as part of your Isaagenix System. Additionally, below we answer some of your most frequently asked questions.

What are the two IsaBiome systems, and how do I know which one is right for me?

IsaBiome is a product line designed to support daily and long-term gut health. Featuring live probiotics and active digestive enzymes, the IsaBiome Daily Digestive Health System is specially formulated to support your personal microbiome while aligning with your diet.

The foods you eat play a major role in determining the makeup of your microbiome. Similarly, digestive enzymes are specific to components of the foods you consume. IsaBiome provides targeted support that matches your diet, helping with digestive comfort during and after meals and keeping your gut microbiome balanced over time.

All IsaBiome products comes in two types. If you consume a varied diet that includes both plant- and animal-sourced foods, Conventional Diet IsaBiome is tailored to meet your needs. If you have a plant-based or vegetarian eating style, Vegetarian Diet IsaBiome is for you.

What are the differences between Conventional Diet and Vegetarian Diet IsaBiome Probiotics?

Many of the same beneficial probiotics are provided in both Conventional Diet and Vegetarian Diet IsaBiome Probiotics. These probiotic strains were selected because they provide broad, general benefits for everyone, although they are provided in different proportions to reflect the influence of different dietary patterns. Other probiotic strains appear only in Conventional Diet IsaBiome Probiotics or Vegetarian Diet IsaBiome Probiotics. These unique, specific strains were selected based on factors related to different dietary patterns.

What are the differences between Conventional Diet and Vegetarian Diet IsaBiome Digestive Enzymes?

Both Conventional Diet and Vegetarian Diet IsaBiome Digestive Enzymes are formulated to provide the right digestive support for the nutrient profile of your diet, based on the foods and meals you eat every day. Conventional diets that include meat or animal-based foods and vegetarian diets that are plant-based each have different nutritional profiles. These different eating styles require the support of different digestive enzymes.

How do I use IsaBiome as part of my Isagenix System?

Although anyone could benefit from using IsaBiome Probiotics or IsaBiome Digestive Enzymes, they were developed to work as part of any Isagenix System to support healthy digestion.

IsaBiome Probiotics complements any Isagenix System as it’s intended for daily use. For those following an Isagenix Weight Loss System, IsaBiome Probiotics can be taken on both Cleanse Days and Shake Days to support digestive and overall health and promote diversity within your personal microbiome.

IsaBiome Digestive Enzymes provides fast-acting digestive support when consumed with a meal on Shake Days or any other day. Because IsaLean® Shake contains its own blend of enzymes, IsaBiome Digestive Enzymes is best used with your 400- to 600-calorie meal or whenever you want added digestive support. Because Cleanse Days involve abstaining from most foods as part of intermittent fasting, there is little need to consume digestive enzymes on Cleanse Days.

What are the benefits of taking an enzyme supplement? Doesn’t my body naturally produce digestive enzymes?

The body naturally produces digestive enzymes, but aging, genetic factors, and other influences may decrease the amount of digestive enzymes that your body can produce. Additionally, there are components of common foods that your body can’t digest on its own, which can lead to digestive discomfort. Supplementing with IsaBiome™ Digestive Enzymes can help you enjoy nutritious, nourishing foods and enhance digestive comfort with your personal diet in mind.

When is the best time to take IsaBiome Digestive Enzymes?

The most effective time to take IsaBiome Digestive Enzymes is with your largest meal of the day. IsaBiome Digestive Enzymes may also be used with meals any time you need additional digestive support.

Can I take more than one capsule of IsaBiome Digestive Enzymes at once?

The recommended way to use IsaBiome Digestive Enzymes is to take one capsule as you begin a meal or when additional digestive support is needed. While taking more than one capsule at a time is safe, consuming additional digestive enzymes may not provide additional benefit.

When is the best time to take IsaBiome Probiotics?

For optimal benefit, take IsaBiome Probiotics daily on an empty stomach. However, IsaBiome Probiotics may be taken at any time of day or with food if necessary.

Can I take more than one capsule of IsaBiome Probiotics at once?

The recommended way to use IsaBiome Probiotics is to take one capsule daily, preferably on an empty stomach. You may consume up to three capsules daily as needed for additional support for digestive and overall health. Consuming more than three capsules daily is unlikely to provide additional benefits and is not recommended.

Why is refrigeration not required for IsaBiome Probiotics?

Moisture and oxygen degrade probiotics, significantly reducing viability and potency. Advanced manufacturing and packaging technologies help ensure the stability and potency of IsaBiome Probiotics. IsaBiome Probiotics undergo a gentle microencapsulation process that involves coating cells with a protective lipid barrier to keep oxygen and moisture from causing damage. Microencapsulated probiotics are sealed in a special protective capsule and packaged in a desiccant bottle that controls moisture to further protect the probiotics, creating a stable probiotic that does not require refrigeration.

What is the suggested minimum age to use IsaBiome Probiotics and IsaBiome Digestive Enzymes?

IsaBiome Probiotics and IsaBiome Digestive Enzymes are recommended for anyone 12 years of age and older.

Are IsaBiome products made with vegetarian ingredients?

Regardless of whether designed for “vegetarian” (plant-based) or “conventional” diets (meat inclusive), all IsaBiome products are formulated with ingredients that are suitable for vegetarians.

Do IsaBiome products contain dairy?

Both varieties of IsaBiome Probiotics display the allergen statement “contains milk ingredients.” The reason is that IsaBiome Probiotics for Conventional Diets is formulated with ingredients derived from dairy. While IsaBiome Probiotics for Vegetarian Diets is not formulated with ingredients derived from dairy, it is produced in a facility where milk ingredients may be present. For that reason, IsaBiome Probiotics may not be appropriate for those who do not include dairy in their diets. Note that IsaBiome Digestive Enzymes for Conventional Diets and IsaBiome Digestive Enzymes for Vegetarian Diets do not contain milk ingredients. See product labels for full allergen information.

Are IsaBiome products vegan?

Neither the IsaBiome Probiotics or IsaBiome Digestive Enzymes are vegan. See product labels for full ingredient disclosure.


To purchase IsaBiome, please visit our Isagenix store: www.ChampionsNutrition.com.


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