Isagenix: Choose Your Way to Cleanse with Cleanse for Life


The blend of ingredients supported by science make Cleanse for Life a one-of-a-kind product.

Few products come close to the nutritional profile of Cleanse for Life®—an herbal drink formulated to nourish the body and support its natural detoxification systems. While the body has pathways to remove toxins from the body, just like any machine, it can become overloaded. The combination of ingredients in Cleanse for Life works synergistically to support the body’s detoxification pathways and help them work more efficiently.

Three phases of detoxification occur within the body to metabolize fat-soluble toxins into less toxic compounds that can safely be removed from the body. Each of these phases requires certain enzymes and bioactive nutrients to do their job (1,2).

Think of it like this: In order for you to drive to work, you need to safely pass through intersections. Stoplights and signs assist you in getting to your destination by signaling you to go straight, stop, or turn. Just as these direct you to your office, various nutrients and enzymes assist in getting toxins out of fat cells, into circulation, and to the liver to be excreted.

You’ll find these nutrients needed to safely remove impurities from the body in Cleanse for Life. The blend of B vitamins, herbs such as burdock root, and plant botanicals including ashwaganda, aloe vera, and turmeric support detoxification pathways (4-6).

Additionally, antioxidant support is needed for optimal detoxification. While we’re most familiar with environmental toxins—pollution, cleaning chemicals, etc.—some toxins are produced within the body from free radicals. Antioxidants help neutralize oxidative stressed caused by toxins. That’s why you’ll find powerful antioxidants like bilberry and blueberry fruit extracts in Cleanse for Life.

There are multiple ways you can incorporate nutrient-rich Cleanse for Life into your diet. But for best results, it’s recommended that you follow some general guidelines.

Daily Cleansing: Daily Cleansing involves drinking Cleanse for Life on a daily basis while still consuming shakes and meals. With Daily Cleansing, the main benefit is providing your body with the polyphenol-rich nutrients and plant extracts in Cleanse for Life. Many who do Daily Cleansing choose to have their Cleanse for Life before they go to bed when the body naturally fasts during sleeping. But really, Cleanse for Life can be consumed any time of the day.

One- or Two-Day Deep Cleansing: Deep Cleansing involves abstaining from eating normal meals and food for one or two days. The equivalent in the scientific literature is termed intermittent fasting. The research supporting intermittent fasting is vast, showing benefit for weight loss, cognitive health, cardiovascular health, and more (7-10).

Instead of only drinking water as some cleanses recommend, Cleanse for Life is taken throughout the day. Other “tools” can be used as well and include Isagenix Snacks!™, IsaDelight Plus™ Milk or Dark chocolates, Ionix® Supreme, e+, and Want More Energy?® (if exercising). These tools are important for overcoming cravings and for maintaining healthy blood sugar levels. Some people may require more to prevent dips in blood sugar that can lead to light-headedness or fatigue*.

While it’s smart to use Cleanse Day tools, it’s important to remember that calories can add up. Use them as needed, and don’t feel bad if sometimes more are needed (or maybe an apple slice or carrot) to be successful. Low-calorie beverages including herbal and green tea as well as t+ Chai are useful tools to help keep you committed to the cleanse. And if you absolutely cannot make it through a Deep Cleanse, break it guiltlessly with an IsaLean® Shake and plan for another time to cleanse. Cleansing is like a skill—the more you do it, the easier it is and the better you become.

As to which is better—a one- or two-day cleanse—they both are good! Any amount of time the body is given a rest from normal digestion of foods and meals is beneficial. Two days of cleansing may bring additional benefit in allowing the body more time to restore and rejuvenate (10), but science shows fasting for just one day can still be beneficial for health through increasing the body’s production of growth hormone, which plays an important role in muscle building, preventing muscle breakdown, and increasing fat burning (11).

No matter if it’s Deep Cleansing for one or two days or Daily Cleansing, Isagenix makes it possible for just about anyone to incorporate this health-benefitting practice into their normal routine. The key is personalization. What works for some may not work for others—just don’t miss out on the nourishment Cleanse for Life provides.

*If any blood sugar or other health issues are a concern, be sure to work with a physician to determine the amount and type of calories that should be consumed throughout a Cleanse Day so blood sugar remains at a safe and healthy level. Cleansing, whether Deep or Daily, may not be suitable for all health conditions.


  1. Liska DJ. The detoxification enzyme systems. Altern Med Rev 1998;3:187-98.
  2. Yang YM, Noh K, Han CY, Kim SG. Transactivation of genes encoding for phase II enzymes and phase III transporters by phytochemical antioxidants. Molecules 2010;15:6332-48.
  3. Vinson JA, Al KH, Andreoli L. Effect of Aloe vera preparations on the human bioavailability of vitamins C and E. Phytomedicine 2005;12:760-5.
  4. Kim BH, Hong SS, Kwon SW et al. Diarctigenin, a lignan constituent from Arctium lappa, down-regulated zymosan-induced transcription of inflammatory genes through suppression of DNA binding ability of nuclear factor-kappaB in macrophages. J Pharmacol Exp Ther 2008;327:393-401.
  5. Eshghinia S, Mohammadzadeh F. The effects of modified alternate-day fasting diet on weight loss and CAD risk factors in overweight and obese women. J Diabetes Metab Disord 2013;12:4.
  6. Ahmad MK, Mahdi AA, Shukla KK et al. Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males. Fertil Steril 2010;94:989-96.
  7. Gozansky et al. Intermittent fasting reduces abdominal obesity and improves cognitive function in obese adults. Obesity Week, 2013; Abstract P-537.
  8. Mattson MP, Wan R. Beneficial effects of intermittent fasting and caloric restriction on the cardiovascular and cerebrovascular systems. J Nutr Biochem 2005;16:129-37.
  9. Varady KA, Hellerstein MK. Alternate-day fasting and chronic disease prevention: a review of human and animal trials. Am J Clin Nutr 2007;86:7-13
  10. Bergamini E, Cavallini G, Donati A, Gori Z. The role of autophagy in aging: its essential part in the anti-aging mechanism of caloric restriction. Ann N Y Acad Sci 2007;1114:69-78.
  11. Intermountain Medical Center. Routine periodic fasting is good for your health, and your heart, study suggests. Science Daily 2011, May 20.


The System Guide for Weight Loss provides all the information you need to get started on Cleanse Days with an easy, step-by-step guide. But how you make cleansing fit with your schedule and personality is a matter of style.

Cleansing in a way that works for you helps to make Cleanse Days a perfect fit for your lifestyle. Here are three Cleanse Day styles you can try on for size.

The Pampered Cleanser

If this is your Cleanse Day style, you think of Cleanse Days as a chance to relax and nurture yourself. Pampered cleansers use Cleanse Days as a break from the everyday routine and as a time to let their bodies rest and recharge.

  • You enjoy drinking your Cleanse for Life® out of your most elegant glasses.
  • If you usually cook for others, Cleanse Days are your night off from the kitchen.
  • You take a hot bath or treat yourself to a massage to make your day especially relaxing.
  • You give yourself permission to sleep in a little or even take a nap, since this is your day to rest, relax, and take care of yourself.

The Busy Cleanser

If this is your Cleanse Day style, you feel like cleansing helps to boost your productivity. After all, if you don’t need to take time out for cooking, eating meals, or cleaning up, you’ll be able to get more done during the day.

  • Whether your day is packed with errands or nonstop meetings, you breeze through your Cleanse Days by checking off your to-do list.
  • Cleanse Days are marked on your calendar so you can avoid scheduling conflicts and plan ahead.
  • You keep a supply of Cleanse for Life handy at your desk or in your bag, so it’s always ready to go when you are.
  • Because you have a lot going on, you set reminders on your phone to help you say on schedule with your next snack or next serving of Cleanse for Life.

The Sporty Cleanser

If this is your cleansing style, you are a fitness enthusiast who has an urge to get moving every day. Sporty cleansers integrate gentle exercise into Cleanse Days because they know that light exercise boosts mood and helps them to feel their best.

  • If temptation strikes, taking a brisk walk is your first choice to help you to stay motivated.
  • Because you train hard during the rest of the week, Cleanse Days are your day to work on flexibility with yoga or stretching exercises.
  • You choose AMPED™ Hydrate as one of your support tools because there’s a good chance you’ll be getting a little sweaty on Cleanse Days.
  • You don’t overdo it! Gentle exercise can be great when you’re cleansing, but you save your hard workouts for days when you are fueling your body for performance.

Customizing your Cleanse Day experience to fit with your personality and lifestyle can be an effective approach for achieving lasting success. These Cleanse Day styles are just a few examples of how you can create a Cleanse Day routine based on the System Guide for Weight Loss to fit your own personal sense of style.

Meet the Adaptogens in Ionix Supreme

Stress affects us every day. Whether from work, finances, or relationships, stress can make us feel overworked and overloaded. But stress affects more than just our mental performance. It has real physical consequences, too, and can eventually lead to poor health and disease.

Stress management methods include exercise, hobbies, or other relaxing activities such as meditation or yoga. Unfortunately, according to a 2006 survey by the American Psychological Association, many Americans are resorting to unhealthy habits when trying to manage stress. Whether it’s alcohol, stimulants or simply overeating, many Americans are in need of finding a positive outlet for stress.

One healthy, effective way of dealing with stress without negative side effects is through the daily use of Adaptogens. From the Greek word “adapto” meaning to adjust, the term Adaptogen is applied to plants that produce special substances originally intended to help them adapt to and overcome stressors in their own environments. Some of these Adaptogens, many of which have been used traditionally in parts of Asia and Europe, are found to have properties that also extend benefits to humans.

Former Soviet Union research scientists Nicolai Lazarev and Israel Brekhman were the first to study Adaptogens scientifically in hopes to provide a natural means of improving strength, energy, and stamina in soldiers, as well as athletes and cosmonauts. Further research found that Adaptogens work by normalizing the body’s functions under stress and taking them daily improves mental and physical performance while reducing fatigue (1,2).

Though all Adaptogens help the body reduce and resist the effects of stress, they each have their own mechanism of action to benefit overall health. And because there’s no toxicity associated with Adaptogens, the more the better.

Here’s a deeper look at the adaptogen blend found in Ionix® Supreme:

Wolfberry (Lycium barbarum) is a red-orange berry of the Solanaceae nightshade family that includes tomato, eggplant, chili pepper, and potato. Ancient herbalists regarded Wolfberry as nourishing to the liver, kidney, and eyes. Modern studies support these traditional claims by showing that the extracts from Wolfberry have antioxidant properties and protect the body from oxidative stress (3-5).

Eleuthero root (Eleutherococcus senticosus) is a small, woody shrub native to Northeastern Asia. It has been used in China for more than 2,000 years as a natural remedy for reducing fatigue. Recent studies have also indicated eleuthero root to help maintain mental and physical performance under stressful conditions such as working in an emergency room (6). 

Rhodiola (Rhodiola rosea) is a plant that grows in the coldest regions of the world, including Northern Asia. It’s been used as an herbal medicine for several centuries in Russia and Scandinavia to increase physical endurance, improve energy levels, and help resist high altitude sickness. In clinical trials Rhodiola has been shown to help strengthen the body’s resistance to stress (7).

Ashwagandha (Withania somnifera), like Wolfberry, is a plant in the Solanaceae nightshade family and is native to the dry regions of India, North Africa, and the Middle East. It’s been an important component in Indian Ayurvedic medicine since ancient times, mostly for its restorative benefits. In recent studies Ashwagandha has demonstrated antioxidant effects (8,9). Studies have also shown it to support healthy brain and immune function (10,11).

Bacopa (Bacopa monniera) is a plant popular in traditional Indian medicine practices for the enhancement of memory and to promote longevity. Preclinical studies have shown it to have antioxidant and adaptogenic effects on the central nervous system (12-14).

Schizandra (Schisandra chinensis) is known as the “five flavor berry” because it contains all five of the basic flavors: sweet, salty, sour, pungent, and bitter. The berry grows as part of a woody vine native to the forests of Northern China and Eastern Russia. It has long been used in Traditional Chinese Medicine to nourish the kidneys and heart. In human studies, schisandra has shown to increase work accuracy and antioxidant protection and decreased feelings of fatigue and exhaustion (15).

The stresses of life are not likely to disappear, but we can provide our body with the nutrition it needs to better manage the physical response to stress. Prime your body daily with the blend of adaptogens in Ionix Supreme for optimal stress protection and overall health.


  1. Panossian A, Wikman G. Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity. Curr Clin Pharmacol 2009;4:198-219.
  2. Panossian A, Wikman G. Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stree-protective activity. Pharmaceuticals 2010; 3: 188-224.
  3. Amagase H, Sun B, Borek C. Lycium barbarum juice improves in vivo antioxidant biomarkers in serum of healthy adults. Nutr Res 2009;29:19-25.
  4. Zhang R, Kang KA, Piao MJ et al. Cytoprotective effect of the fruits of Lycium chinenseMiller against oxidative stress-induced hepatotoxicity. J Ethnopharmacol 2010;130:299-306.
  5. Amagase H, Nance DM. A randomized, double-blind, placebo-controlled, clinical study of the general effects of a standardized Lycium barbarum. J Altern Complement Med 2008;14:403-12. Jeyanthi T, Subramanian P. Nephroprotective effect of Withania somnifera: a dose-dependent study. Ren Fail 2009;31:814-21.
  6. Kuo J, Chen KW, Cheng IS, Tsai PH, Lu YJ, Lee NY. The effect of eight weeks of supplementation with Eleutherococcus senticosus on endurance capacity and metabolism in human. Chin J Physiol2010;53:105-11.
  7. Darbinyan V, Kteyan A, Panossian A, Gabrielian E, Wikman G, Wagner H. Rhodiola rosea in stress induced fatigue–a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty. Phytomedicine 2000;7:365-71.
  8. Jayaprakasam B, Padmanabhan K, Nair MG. Withanamides in Withania somnifera fruit protect PC-12 cells from beta-amyloid responsible for Alzheimer’s disease. Phytother Res 2010;24:859-63.
  9. Auddy B, et al. Standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans: a double-blind, randomized, placebo-controlled study. JANA 2008; 11:50-56.
  10. Ziauddin M, Phansalkar N, Patki P, Diwanay S, Patwardhan B. Studies on the immunomodulatory effects of Ashwagandha. J Ethnopharmacol 1996;50:69-76.
  11. Davis L, Kuttan G. Immunomodulatory activity of Withania somnifera. J Ethnopharmacol 2000;71:193-200.
  12. Uabundit N, Wattanathorn J, Mucimapura S, Ingkaninan K. Cognitive enhancement and neuroprotective effects of Bacopa monnieri in Alzheimer’s disease model. J Ethnopharmacol 2010;127:26-31. doi: 10.1016/j.jep.2009.09.056
  13. Morgan A, Stevens J. Does Bacopa monnieri improve memory performance in older persons? Results of a randomized, placebo-controlled, double-blind trial. J Altern Complement Med 2010;16:753-9.
  14. Roodenrys S, Booth D, Bulzomi S, Phipps A, Micallef C, Smoker J. Chronic effects of Brahmi (Bacopa monnieri) on human memory. Neuropsychopharmacology 2002;27:279-81.
  15. Aslanyan G, et al. Double-blind, placebo-controlled, randomized study of single dose effects of ADAPT-232 on cognitive functions. Phytomedicine 2010.


Comments are closed.

%d bloggers like this: