Isagenix Clinical Research Studies

The Isagenix commitment to scientific research that adds to the understanding of the relationship between diet, nutrition, and health is one of the factors that sets the company apart.

By partnering with well-respected universities and laboratories in funding and conducting clinical studies, Isagenix is contributing to evidence-based nutrition research while also providing clinical substantiation for Isagenix systems for healthy weight loss and healthy living.

Since its inception, Isagenix has led with science-backed products, and now will continue to put Isagenix products to the test in discovering how they can benefit health. For a look at some of the research Isagenix has funded, visit this page regularly as new scientific studies and papers will be posted as they are published.

(Click images to see the peer-reviewed publications)

Weight Loss: 

Weight loss Study at University of Illinois at Chicago

Summary of the results.


Study 1






Long-Term Weight Loss Study at Skidmore College 

Summary of results.

Summary of toxin study results.








Energy & Performance:

Women’s Performance Study at Skidmore College

Summary of the results. 



Men’s Performance Study at Skidmore College

Summary of results.

Mens performance study image






Healthy Aging: 

Product B IsaGenesis Study at Arizona State University

Summary of results.








Klempel MC, Kroeger, CM, Bhutani S et al. Intermittent fasting combined with calorie restriction is effective for weight loss and cardio-protection in obese women. Nutr J 2012 11:98. doi: 10.1186/1475-2891-11-98.

Kroeger CM, Klempel MC, Bhutani S et al. Improvement in coronary heart disease risk factors during an intermittent fasting/calorie restriction regimen: Relationship to adipokine modulations. Nutr Metab 2012;9:98. doi: doi: 10.1186/1743-7075-9-98

Arciero PJ, Edmonds R, He F, Ward E, Gumpricht E, Mohr A, Ormsbee MJ, Astrup A.  Protein-pacing caloric-restriction enhances body composition similarly in obese men and women during weight Loss and sustains efficacy during long-term weight maintenance. Nutrients 2016, 8(8), 476; doi: 10.3390/nu8080476

Li Z, He F, Tinsley G et al. Comparison of high-protein, intermittent-fasting low-calorie diet and heart healthy diet for vascular health of the obese Front. Physiol. 7:350. doi: 10.3389/fphys.2016.00350

Arciero PJ, Ives SJ, Norton C, Escudero D, Minicucci O, O’Brien G, Paul M, Ormsbee MJ, Miller V, Sheridan C, He F. Protein-pacing and multi-component exercise training improved physical performance outcomes in exercise-trained women: PRISE 3 study. Nutrients 2016, 8(6), 332; doi:10.3390/nu8060332

Ives SJ, Norton C, Miller V, Minicucci O, Robinson J, O’Brien G, Escudero D, Paul M, Sheridan C, Curran K, Rose K, Robinson N, He F & Arciero PJ. Multi-modal exercise training and protein-pacing enhances physical performance adaptations independent of growth hormone and BDNF but may be dependent on IGF-1 in exercise-trained men. Growth Horm IGF Res. 2016 Oct 24. doi: 10.1016/j.ghir.2016.10.002

Sweazea KL, Johnston CS, Knurick J, Bliss CD. Plant-based nutraceutical increases plasma catalase activity in healthy participants: A small double-blind, randomized, placebo-controlled, proof of concept trial. J Diet Suppl. 2016;0,0:1-14. doi: 10.1080/19390211.2016.1207742

Isagenix Science Roundup

The news generated by scientific studies funded by Isagenix has gained some recent interest from popular media around the web. Here’s a roundup of some of our favorite articles that have appeared related to results in performance and weight loss.

Daily Mail

Is ‘protein pacing’ the secret to a svelte summer body? Science-backed regime is PROVEN to give you a flatter stomach and a leaner frame – April 17, 2017


How to Get Into the Best Shape of Your Life, According to Science – March 27, 2017


Fitness: Dr. Paul Arciero Helps You Keep Your Eyes on the PRISE – March 2, 2017

Muscle & Fitness

Here’s How You Can Lose Weight Long-Term While Cleaning Toxins Out of Your Body

Men’s Journal

Protein-Pacing: The Science Backed Secret to Getting Fitter Faster

Men’s Fitness

Think you’re fit? Scientists just figured out how to become even fitter – February 8, 2017

Here’s how you can lose weight long-term while cleaning toxins out of your body – January 27, 2017

Science Daily

Diet quality improves fitness among the fittest – February 6, 2017

Diet helps shed pounds, release toxins and reduce oxidative stress – January 11, 2017


The Athlete’s Guide to Protein – April 27, 2017


Meet “Protein Pacing,” the Eating Technique That Can Jump-Start Your Weight Loss – March 28, 2017

Mind Body Green

New Study Shows A Protein-Pacing + IF Combo Promotes Detox & Weight Loss – January 13, 2017

To Get In The Best Shape Of Your Life: Stop Calorie Counting, Start Protein-Pacing – February 8, 2017

Fit Style Life

Want To Improve Your Health In Every Way? Try Protein-Pacing – February 7, 2017

Eat This, Not That!

How to Eat Protein for Optimal Fat Loss

Fox News

How to get into the best shape of your life, according to science – April 6, 2017


Science says this is the best eating plan to get lean

Breaking Muscle

PRISE: The Regimen Of Champions

Health Buzz Feed

How Balanced Diet Helps Shed Pounds, Release Stress – Research – January 12, 2017

Tech Times

How Diet Quality Makes The Fittest Fitter: Study – February 9, 2017

Paste Magazine

Bodies in Balance: PRISE Protocol – May 8 2017

The views expressed by the authors of the linked articles are not necessarily those of Isagenix.

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